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Query: NC_002935:2103677:2115398 Corynebacterium diphtheriae NCTC 13129, complete genome

Start: 2115398, End: 2115535, Length: 138

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016790:2027332:203608120360812036218138Corynebacterium diphtheriae VA01 chromosome, complete genome2-hydroxy-6-oxononadienedioate/2-hydroxy-6- oxononatrienedioate hydrolase7e-1992.4
NC_016786:2059564:207171120717112071848138Corynebacterium diphtheriae HC01 chromosome, complete genome7e-1889.4
NC_016782:2058967:207111420711142071251138Corynebacterium diphtheriae 241 chromosome, complete genomeputative hydrolase remnant7e-1889.4
NC_016788:2115428:212458421245842124697114Corynebacterium diphtheriae HC04 chromosome, complete genome2e-1478.2
NC_014098:2332938:235608723560872356923837Bacillus tusciae DSM 2912 chromosome, complete genomealpha/beta hydrolase fold protein7e-0752.8