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Query: NC_002935:181902:182762 Corynebacterium diphtheriae NCTC 13129, complete genome

Start: 182762, End: 183877, Length: 1116

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016789:199503:2067692067692078841116Corynebacterium diphtheriae PW8 chromosome, complete genomeimmunity-specific protein Beta3715e-178623
NC_016785:161498:168763168763169506744Corynebacterium diphtheriae CDCE 8392 chromosome, complete genomeimmunity-specific protein Beta3715e-114411
NC_016785:161498:169503169503169877375Corynebacterium diphtheriae CDCE 8392 chromosome, complete genomeimmunity-specific protein beta3711e-61236
NC_015683:1270782:1285754128575412868751122Corynebacterium ulcerans BR-AD22 chromosome, complete genomeimmunity-specific protein beta3713e-53209
NC_016799:198091:2059902059902071951206Corynebacterium diphtheriae 31A chromosome, complete genomeimmunity-specific protein Beta3713e-38159