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Query: NC_002935:1237585:1267163 Corynebacterium diphtheriae NCTC 13129, complete genome

Start: 1267163, End: 1267558, Length: 396

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016801:1255611:128598712859871286382396Corynebacterium diphtheriae C7 (beta) chromosome, complete genomehypothetical protein1e-63241
NC_016785:1193471:122097512209751221370396Corynebacterium diphtheriae CDCE 8392 chromosome, complete genomehypothetical protein1e-63241
NC_016799:1268706:129620912962091296604396Corynebacterium diphtheriae 31A chromosome, complete genomehypothetical protein4e-63239
NC_016789:1257392:128489412848941285289396Corynebacterium diphtheriae PW8 chromosome, complete genomehypothetical protein4e-63239
NC_016782:1227246:124092712409271241322396Corynebacterium diphtheriae 241 chromosome, complete genomehypothetical protein6e-63238
NC_016786:1218032:124089612408961241291396Corynebacterium diphtheriae HC01 chromosome, complete genomehypothetical protein6e-63238
NC_016787:1207488:123035212303521230747396Corynebacterium diphtheriae HC03 chromosome, complete genomehypothetical protein6e-63238
NC_016788:1214026:124033912403391240734396Corynebacterium diphtheriae HC04 chromosome, complete genomehypothetical protein6e-63238
NC_016790:1177349:120772912077291208124396Corynebacterium diphtheriae VA01 chromosome, complete genomehypothetical protein6e-63238
NC_016802:1212726:124022912402291240624396Corynebacterium diphtheriae HC02 chromosome, complete genomehypothetical protein6e-63238
NC_016800:1243000:126932512693251269720396Corynebacterium diphtheriae BH8 chromosome, complete genomehypothetical protein8e-63238