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Query: NC_002935:1237585:1245768 Corynebacterium diphtheriae NCTC 13129, complete genome

Start: 1245768, End: 1246727, Length: 960

Host Lineage: Corynebacterium diphtheriae; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated in 1997 from the pharyngeal membrane of a 72-year-old unimmunized UK female with clinical diphtheria acquired during a short Baltic cruise. Causative agent of diphtheria. They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. This organism is the best known and most widely studied species of the genus. It is the causal agent of the disease diphtheria, a deadly infectious disease spreading from person to person by respiratory droplets from the throat through coughing and sneezing. In the course of infection, the bacteria invade and colonize tissues of the upper respiratory tract, proliferate and produce exotoxin that inhibits protein synthesis and causes local lesions and systemic degenerative changes in the heart, muscles, peripheral nerves, liver and other vital organs. In 1951, Victor Freeman discovered that pathogenic (toxigenic) strains. Moreover, later it was found that the gene for toxin production is located in the DNA of the B-type phage.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016790:1177349:118633311863331187292960Corynebacterium diphtheriae VA01 chromosome, complete genomehypothetical protein0660
NC_016788:1214026:121894312189431219902960Corynebacterium diphtheriae HC04 chromosome, complete genomehypothetical protein0660
NC_016787:1207488:120895612089561209915960Corynebacterium diphtheriae HC03 chromosome, complete genomehypothetical protein0660
NC_016786:1218032:121950012195001220459960Corynebacterium diphtheriae HC01 chromosome, complete genomehypothetical protein0660
NC_016783:1239293:124540012454001246359960Corynebacterium diphtheriae INCA 402 chromosome, complete genomehypothetical protein0660
NC_016785:1193471:1199578119957812006961119Corynebacterium diphtheriae CDCE 8392 chromosome, complete genomehypothetical protein0659
NC_016801:1255611:126459312645931265552960Corynebacterium diphtheriae C7 (beta) chromosome, complete genomehypothetical protein0657
NC_016789:1257392:126349912634991264458960Corynebacterium diphtheriae PW8 chromosome, complete genomehypothetical protein0654
NC_016800:1243000:124793012479301248889960Corynebacterium diphtheriae BH8 chromosome, complete genomehypothetical protein0654
NC_016802:1212726:121883312188331219792960Corynebacterium diphtheriae HC02 chromosome, complete genomehypothetical protein0654
NC_016799:1268706:127481312748131275772960Corynebacterium diphtheriae 31A chromosome, complete genomehypothetical protein0652
NC_013093:2471574:249031724903172491282966Actinosynnema mirum DSM 43827, complete genomeputative transcriptional regulator protein1e-29130
NC_003155:7979050:8001187800118780022271041Streptomyces avermitilis MA-4680, complete genomehypothetical protein2e-1273.9
NC_013729:5497814:549928354992835500260978Kribbella flavida DSM 17836, complete genometranscriptional regulator protein-like protein2e-1066.6
NC_013174:1366786:137721913772191378202984Jonesia denitrificans DSM 20603, complete genomehypothetical protein7e-0755.1