Pre_GI: BLASTP Hits

Some Help

Query: NC_000962:3781501:3790156 Mycobacterium tuberculosis H37Rv, complete genome

Start: 3790156, End: 3790809, Length: 654

Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain has been derived from the original human-lung H37 isolate in 1934, and has been used extensively worldwide in biomedical research. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:3754000:375940837594083760061654Mycobacterium tuberculosis RGTB327 chromosome, complete genomeputative HAD superfamily hydrolase1e-120432
NC_002945:3735141:374379637437963744449654Mycobacterium bovis AF2122/97, complete genomehypothetical protein1e-120432
NC_009565:3793976:380263138026313803284654Mycobacterium tuberculosis F11, complete genomehypothetical protein1e-120432
NC_012207:3766978:377563337756333776286654Mycobacterium bovis BCG str. Tokyo 172, complete genomehypothetical protein1e-120432
NC_008769:3769065:377772037777203778373654Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein1e-120432
NC_002755:3773734:378238937823893783042654Mycobacterium tuberculosis CDC1551, complete genomehydrolase, haloacid dehalogenase-like family1e-120432
NC_009525:3794000:379927937992793799932654Mycobacterium tuberculosis H37Ra, complete genomehypothetical protein1e-120432
NC_012943:3777371:378602637860263786679654Mycobacterium tuberculosis KZN 1435 chromosome, complete genomehypothetical protein1e-120432
NC_016768:3774105:378276037827603783413654Mycobacterium tuberculosis KZN 4207 chromosome, complete genomehypothetical protein1e-120432
NC_016804:3753243:375708537570853757738654Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein1e-120432
NC_015848:3851230:385988438598843860537654Mycobacterium canettii CIPT 140010059, complete genomehypothetical protein4e-120430
NC_019950:3818000:382327538232753823928654Mycobacterium canettii CIPT 140060008 complete genomehypothetical protein4e-120430
NC_014761:1588755:160430216043021604967666Oceanithermus profundus DSM 14977 chromosome, complete genomehad-superfamily hydrolase, subfamily ia, variant 32e-1685.5
NC_014550:3263783:326643532664353267112678Arthrobacter arilaitensis Re117, complete genomehaloacid dehalogenase-like family hydrolase2e-1066.2
NC_014210:2372813:237500823750082375742735Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,HAD-superfamily hydrolase, subfamily IA, variant 13e-1065.5
NC_016791:1266404:127043312704331271113681Clostridium sp. BNL1100 chromosome, complete genomebeta-phosphoglucomutase6e-1064.3
NC_011898:3772899:378689237868923787551660Clostridium cellulolyticum H10, complete genomebeta-phosphoglucomutase3e-0962
NC_012108:3922511:392624439262443926930687Desulfobacterium autotrophicum HRM2, complete genomeputative (S)-2-haloacid dehalogenase (2-haloalkanoic acid dehalogenase) (L-2-haloacid dehalogenase) (DEHC)1e-0859.7
NC_011080:4177443:419707741970774197676600Salmonella enterica subsp. enterica serovar Newport str. SL254,phosphatase YihX3e-0858.9
NC_010067:3538169:356629935662993566898600Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein3e-0858.9
NC_008262:297960:320522320522321175654Clostridium perfringens SM101, complete genomehaloacid dehalogenase, IA family protein6e-0857.8
NC_013282:4312791:433241243324124333011600Cronobacter turicensis, complete genomePhosphatase yihX8e-0857.4
NC_016109:3875617:387905938790593879682624Kitasatospora setae KM-6054, complete genomeputative hydrolase9e-0857
NC_006624:405966:408815408815409468654Thermococcus kodakarensis KOD1, complete genomehydrolase, HAD superfamily1e-0756.6
NC_012039:257962:276720276720277355636Campylobacter lari RM2100, complete genomeHAD-superfamily hydrolase1e-0756.6
NC_013525:556036:562936562936563637702Thermobaculum terrenum ATCC BAA-798 chromosome 1, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 32e-0755.8
NC_015434:2460053:246815624681562468800645Verrucosispora maris AB-18-032 chromosome, complete genomeHAD family hydrolase2e-0755.8
NC_015275:443213:447207447207447866660Clostridium lentocellum DSM 5427 chromosome, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 33e-0755.5
NC_015578:2341026:234102623410262341655630Treponema primitia ZAS-2 chromosome, complete genomeHAD superfamily hydrolase5e-0754.7
NC_009380:2253500:226026222602622260909648Salinispora tropica CNB-440 chromosome, complete genomeHAD family hydrolase6e-0754.3
NC_008261:304000:325782325782326435654Clostridium perfringens ATCC 13124, complete genomehaloacid dehalogenase, IA family protein7e-0753.9
NC_003366:332500:354420354420355073654Clostridium perfringens str. 13, complete genomehypothetical protein7e-0753.9
NC_014655:614874:631843631843632481639Leadbetterella byssophila DSM 17132 chromosome, complete genomebeta-phosphoglucomutase8e-0753.9
NC_013523:2560000:258197225819722582649678Sphaerobacter thermophilus DSM 20745 chromosome 1, complete genomeHAD-superfamily hydrolase, subfamily IA, variant 19e-0753.5
NC_007614:2675302:269663426966342697317684Nitrosospira multiformis ATCC 25196 chromosome 1, completephosphoglycolate phosphatase1e-0653.1
NC_019673:7951493:795430679543067955043738Saccharothrix espanaensis DSM 44229 complete genomeHAD-superfamily hydrolase, subfamily IA, variant 11e-0653.1
NC_014720:2420455:244171424417142442478765Caldicellulosiruptor kronotskyensis 2002 chromosome, completebeta-phosphoglucomutase family hydrolase2e-0652.8
NC_011147:1573470:159101315910131591681669Salmonella enterica subsp. enterica serovar Paratyphi A str2-deoxyglucose-6-phosphatase2e-0652.8
NC_006511:1579776:159583215958321596500669Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCputative hydrolase2e-0652.8
NC_004088:4202247:422097542209754221565591Yersinia pestis KIM, complete genomephosphatase2e-0652.4
NC_017265:4065625:408435340843534084943591Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,phosphatase2e-0652.4
NC_010102:1703172:171922617192261719894669Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein2e-0652.4
NC_011205:1938574:195461719546171955285669Salmonella enterica subsp. enterica serovar Dublin str. CT_020218532-deoxyglucose-6-phosphatase2e-0652.4
NC_012811:410776:414397414397415077681Methylobacterium extorquens AM1 megaplasmid, complete sequenceputative Hydrolase (HAD superfamily)4e-0651.6
NC_014721:373607:388190388190388861672Caldicellulosiruptor kristjanssonii 177R1B chromosome, completebeta-phosphoglucomutase family hydrolase4e-0651.6
NC_013162:811763:825589825589826212624Capnocytophaga ochracea DSM 7271, complete genomebeta-phosphoglucomutase5e-0651.2
NC_015760:343874:363219363219363857639Streptococcus salivarius CCHSS3, complete genomeputative sugar phosphatase of HAD family5e-0651.2
NC_014910:4207227:422720142272014227974774Alicycliphilus denitrificans BC chromosome, complete genomephosphoglycolate phosphatase5e-0651.2
NC_011274:1850086:186613918661391866807669Salmonella enterica subsp. enterica serovar Gallinarum str. 287/912-deoxyglucose-6-phosphatase7e-0650.8
NC_011294:1810285:182632818263281826996669Salmonella enterica subsp. enterica serovar Enteritidis str2-deoxyglucose-6-phosphatase7e-0650.8
NC_016810:1358456:135919313591931359861669Salmonella enterica subsp. enterica serovar Typhimurium strputative hydrolase7e-0650.8
NC_016856:1411579:141231614123161412984669Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S2-deoxyglucose-6-phosphatase7e-0650.8
NC_016857:1358456:135919313591931359861669Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/742-deoxyglucose-6-phosphatase7e-0650.8
NC_016860:1399290:140002714000271400695669Salmonella enterica subsp. enterica serovar Typhimurium str2-deoxyglucose-6-phosphatase7e-0650.8
NC_016863:1359769:136050613605061361174669Salmonella enterica subsp. enterica serovar Typhimurium str. UK-12-deoxyglucose-6-phosphatase7e-0650.8
NC_003197:1401603:140234014023401403008669Salmonella typhimurium LT2, complete genomeputative enzyme7e-0650.8