Pre_GI: BLASTP Hits

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Query: NC_000962:3474000:3479171 Mycobacterium tuberculosis H37Rv, complete genome

Start: 3479171, End: 3479683, Length: 513

Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain has been derived from the original human-lung H37 isolate in 1934, and has been used extensively worldwide in biomedical research. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:3466809:347321534732153473727513Mycobacterium tuberculosis RGTB327 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC5e-78289
NC_012207:3421144:342630834263083426820513Mycobacterium bovis BCG str. Tokyo 172, complete genomemolybdenum cofactor biosynthesis protein C5e-78289
NC_002945:3429315:343571934357193436231513Mycobacterium bovis AF2122/97, complete genomemolybdenum cofactor biosynthesis protein C5e-78289
NC_009565:3485772:349093634909363491448513Mycobacterium tuberculosis F11, complete genomemolybdenum cofactor biosynthesis protein C moaC15e-78289
NC_008769:3427254:343365834336583434170513Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomeputative molybdenum cofactor biosynthesis protein C moaC15e-78289
NC_009525:3484924:349132734913273491839513Mycobacterium tuberculosis H37Ra, complete genomemolybdenum cofactor biosynthesis protein C15e-78289
NC_002755:3465582:347496834749683475480513Mycobacterium tuberculosis CDC1551, complete genomemolybdenum cofactor biosynthesis protein C5e-78289
NC_016804:3407859:341302334130233413535513Mycobacterium bovis BCG str. Mexico chromosome, complete genomemolybdenum cofactor biosynthesis protein C5e-78289
NC_015672:1921023:193664119366411937117477Flexistipes sinusarabici DSM 4947 chromosome, complete genomemolybdenum cofactor biosynthesis protein C1e-35149
NC_011420:69843:898158981590324510Rhodospirillum centenum SW, complete genomemolybdenum cofactor biosynthesis protein C1e-35148
NC_013939:441921:448237448237448713477Deferribacter desulfuricans SSM1, complete genomemolybdenum cofactor biosynthesis protein C3e-35147
NC_018870:115982:161090161090161587498Thermacetogenium phaeum DSM 12270 chromosome, complete genomemolybdenum cofactor biosynthesis protein C3e-34144
NC_019978:1244000:125965412596541260574921Halobacteroides halobius DSM 5150, complete genomemolybdenum cofactor biosynthesis protein MoaC5e-33140
NC_007644:2205599:223177822317782232281504Moorella thermoacetica ATCC 39073, complete genomemolybdenum cofactor biosynthesis protein C7e-33139
NC_009617:2304390:231494623149462315425480Clostridium beijerinckii NCIMB 8052 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC6e-33139
NC_013889:2603914:260463226046322605123492Thioalkalivibrio sp. K90mix chromosome, complete genomemolybdenum cofactor biosynthesis protein C2e-32138
NC_012791:5496175:549779554977955498286492Variovorax paradoxus S110 chromosome 1, complete genomemolybdenum cofactor biosynthesis protein C6e-32136
NC_010718:517473:527786527786528265480Natranaerobius thermophilus JW/NM-WN-LF, complete genomeGTP cyclohydrolase subunit MoaC1e-31135
NC_011830:1504497:150943815094381509929492Desulfitobacterium hafniense DCB-2, complete genomemolybdenum cofactor biosynthesis protein C2e-31135
NC_009699:2116500:212385421238542124333480Clostridium botulinum F str. Langeland chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC4e-31134
NC_017297:2114222:212395621239562124435480Clostridium botulinum F str. 230613 chromosome, complete genomemolybdenum cofactor biosynthesis protein C4e-31134
NC_012563:2203037:221220122122012212680480Clostridium botulinum A2 str. Kyoto, complete genomemolybdenum cofactor biosynthesis protein C3e-31134
NC_009495:2056546:206571020657102066189480Clostridium botulinum A str. ATCC 3502 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC3e-31134
NC_009697:1985187:199435119943511994830480Clostridium botulinum A str. ATCC 19397 chromosome, completemolybdenum cofactor biosynthesis protein MoaC3e-31134
NC_009698:1985404:199456819945681995047480Clostridium botulinum A str. Hall chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC3e-31134
NC_008752:5213431:522102752210275221515489Acidovorax avenae subsp. citrulli AAC00-1, complete genomemolybdenum cofactor biosynthesis protein C3e-31134
NC_010516:2064027:207378620737862074265480Clostridium botulinum B1 str. Okra, complete genomemolybdenum cofactor biosynthesis protein C5e-31133
NC_021182:401129:411442411442411918477Clostridium pasteurianum BC1, complete genomemolybdenum cofactor biosynthesis protein MoaC1e-30132
NC_007973:499606:514059514059514538480Ralstonia metallidurans CH34 chromosome 1, complete sequencemolybdenum cofactor biosynthesis protein C1e-30132
NC_015138:5276857:528368452836845284178495Acidovorax avenae subsp. avenae ATCC 19860 chromosome, completemolybdenum cofactor biosynthesis protein C1e-30132
NC_010520:2171584:218329121832912183770480Clostridium botulinum A3 str. Loch Maree, complete genomemolybdenum cofactor biosynthesis protein C8e-31132
NC_014931:6415940:641800064180006418488489Variovorax paradoxus EPS chromosome, complete genomemolybdenum cofactor biosynthesis protein C7e-31132
NC_014614:554949:560087560087560563477Clostridium sticklandii, complete genomemolybdopterin biosynthesis, protein C2e-30131
NC_012967:786534:811196811196811681486Escherichia coli B str. REL606 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC7e-30129
NC_017096:1081904:111144111114411111920480Caldisericum exile AZM16c01, complete genomemolybdenum cofactor biosynthesis protein C1e-29129
NC_011901:3072817:309300030930003093485486Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completemolybdenum cofactor biosynthesis protein C1e-29129
NC_015563:6357653:637254763725476373035489Delftia sp. Cs1-4 chromosome, complete genomemolybdenum cofactor biosynthesis protein C2e-29128
NC_016112:3840053:384518238451823845658477Methylomicrobium alcaliphilum chromosome, complete genomemolybdenum cofactor biosynthesis protein C2e-29127
NC_008781:4178115:418372941837294184250522Polaromonas naphthalenivorans CJ2, complete genomemolybdenum cofactor biosynthesis protein C3e-29127
NC_010002:960027:967372967372967842471Delftia acidovorans SPH-1, complete genomemolybdenum cofactor biosynthesis protein C3e-29127
NC_015422:4822636:483029048302904830775486Alicycliphilus denitrificans K601 chromosome, complete genomemolybdenum cofactor biosynthesis protein C8e-29126
NC_014624:1349950:136044013604401360937498Eubacterium limosum KIST612 chromosome, complete genomemolybdenum cofactor biosynthesis protein C4e-28124
NC_014632:1404000:142030614203061420773468Ilyobacter polytropus DSM 2926 chromosome, complete genomeGTP cyclohydrolase subunit MoaC3e-28124
NC_014006:850763:852540852540853025486Sphingobium japonicum UT26S chromosome 1, complete genomemolybdenum cofactor biosynthesis protein C2e-28124
NC_008699:833737:836359836359836850492Nocardioides sp. JS614, complete genomemolybdenum cofactor biosynthesis protein C5e-28123
NC_020272:3325000:334098333409833341495513Bacillus amyloliquefaciens IT-45, complete genomemolybdenum cofactor biosynthesis protein MoaC1e-27122
NC_011992:3615517:362305036230503623541492Acidovorax ebreus TPSY, complete genomemolybdenum cofactor biosynthesis protein C1e-27122
NC_013166:1409790:142442614244261424914489Kangiella koreensis DSM 16069, complete genomemolybdenum cofactor biosynthesis protein C1e-26119
NC_017068:2604876:262472326247232625199477Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative molybdenum cofactor biosynthesis protein C1e-26119
NC_014166:3072703:307975030797503080220471Arcobacter nitrofigilis DSM 7299 chromosome, complete genomemolybdenum cofactor biosynthesis protein C2e-26118
NC_015161:36668:500345003450513480Deinococcus proteolyticus MRP chromosome, complete genomemolybdenum cofactor biosynthesis protein C2e-26118
NC_005835:1345790:136038213603821360855474Thermus thermophilus HB27, complete genomemolybdenum cofactor biosynthesis protein C4e-26117
NC_009480:2580429:261660326166032617097495Clavibacter michiganensis subsp. michiganensis NCPPB 382, completeputative molybdenum cofactor biosynthesis protein4e-26117
NC_010001:1806000:182309718230971823588492Clostridium phytofermentans ISDg, complete genomemolybdenum cofactor biosynthesis protein C8e-26116
NC_017243:1558000:156008915600891560538450Brachyspira intermedia PWS/A chromosome, complete genomeMolybdenum cofactor biosynthesis protein C8e-26116
NC_015677:3965716:397333139733313973783453Ramlibacter tataouinensis TTB310 chromosome, complete genomemolybdenum cofactor biosynthesis protein C7e-26116
NC_016148:1021138:105011810501181050609492Thermovirga lienii DSM 17291 chromosome, complete genomeGTP cyclohydrolase subunit MoaC1e-25115
NC_010674:1170264:119195411919541192433480Clostridium botulinum B str. Eklund 17B, complete genomemolybdenum cofactor biosynthesis protein C5e-25113
NC_017080:2379551:2397098239709823981501053Phycisphaera mikurensis NBRC 102666, complete genomemolybdenum cofactor biosynthesis bifunctional protein MoaCB8e-25112
NC_016641:3058571:305926930592693059757489Paenibacillus terrae HPL-003 chromosome, complete genomemolybdenum cofactor biosynthesis protein C3e-24111
NC_014330:169862:169862169862170314453Brachyspira pilosicoli 95/1000 chromosome, complete genomemolybdenum cofactor biosynthesis protein C1e-23108
NC_008025:316302:340114340114340608495Deinococcus geothermalis DSM 11300, complete genomemolybdenum cofactor biosynthesis protein C1e-23108
NC_005125:3570385:358866335886633589187525Gloeobacter violaceus PCC 7421, complete genomemolybdenum cofactor biosynthesis protein C5e-23106
NC_014335:4442500:445041944504194450904486Bacillus cereus biovar anthracis str. CI chromosome, completemolybdenum cofactor biosynthesis protein C1e-22105
NC_008600:4509793:451691445169144517399486Bacillus thuringiensis str. Al Hakam, complete genomemolybdenum cofactor biosynthesis1e-22105
NC_005945:4508304:451570345157034516188486Bacillus anthracis str. Sterne, complete genomemolybdenum cofactor biosynthesis protein C1e-22105
NC_016771:4445815:445326044532604453745486Bacillus cereus NC7401, complete genomemolybdenum cofactor biosynthesis protein MoaC1e-22105
NC_011969:4432454:443940944394094439894486Bacillus cereus Q1 chromosome, complete genomemolybdenum cofactor biosynthesis protein moac1e-22105
NC_011658:4492356:449947744994774499962486Bacillus cereus AH187 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC1e-22105
NC_003909:4484278:449319844931984493683486Bacillus cereus ATCC 10987, complete genomemolybdenum cofactor biosynthesis protein C1e-22105
NC_003997:4507939:451501445150144515499486Bacillus anthracis str. Ames, complete genomemolybdenum cofactor biosynthesis protein C1e-22105
NC_007530:4507742:451514145151414515626486Bacillus anthracis str. 'Ames Ancestor', complete genomemolybdenum cofactor biosynthesis protein C1e-22105
NC_012472:4515909:452303145230314523516486Bacillus cereus 03BB102, complete genomemolybdenum cofactor biosynthesis protein C1e-22105
NC_017200:4520482:452760245276024528087486Bacillus thuringiensis serovar finitimus YBT-020 chromosome,molybdenum cofactor biosynthesis protein MoaC1e-22105
NC_005957:4502733:451017845101784510663486Bacillus thuringiensis serovar konkukian str. 97-27, completemolybdenum cofactor biosynthesis protein C1e-22105
NC_016779:4475425:448254744825474483032486Bacillus cereus F837/76 chromosome, complete genomeMolybdenum cofactor biosynthesis protein MoaC1e-22105
NC_012659:4507966:451504145150414515526486Bacillus anthracis str. A0248, complete genomemolybdenum cofactor biosynthesis protein MoaC1e-22105
NC_012581:4509491:451656645165664517051486Bacillus anthracis str. CDC 684 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC1e-22105
NC_011773:4569600:457848545784854578970486Bacillus cereus AH820 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC1e-22105
NC_006274:4563455:457057645705764571061486Bacillus cereus E33L, complete genomemolybdenum cofactor biosynthesis protein C1e-22105
NC_011772:4638000:464461846446184645103486Bacillus cereus G9842, complete genomemolybdenum cofactor biosynthesis protein MoaC3e-22104
NC_004722:4645678:465459046545904655075486Bacillus cereus ATCC 14579, complete genomemolybdenum cofactor biosynthesis protein C3e-22104
NC_011725:4671432:467887546788754679360486Bacillus cereus B4264 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC3e-22104
NC_014171:4560061:456896945689694569454486Bacillus thuringiensis BMB171 chromosome, complete genomemolybdenum cofactor biosynthesis protein C3e-22104
NC_017208:4692478:469963246996324700117486Bacillus thuringiensis serovar chinensis CT-43 chromosome, completemolybdenum cofactor biosynthesis protein C3e-22104
NC_010184:4532262:453972445397244540209486Bacillus weihenstephanensis KBAB4, complete genomemolybdenum cofactor biosynthesis protein C3e-22104
NC_016783:429162:437742437742438209468Corynebacterium diphtheriae INCA 402 chromosome, complete genomemolybdenum cofactor biosynthesis protein C8e-22103
NC_014958:629459:654112654112654612501Deinococcus maricopensis DSM 21211 chromosome, complete genomemolybdenum cofactor biosynthesis protein C2e-2098.6
NC_007508:1221500:124034012403401240837498Xanthomonas campestris pv. vesicatoria str. 85-10, complete genomemolybdenum cofactor biosynthesis protein C9e-2096.3
NC_014147:765941:766182766182766673492Moraxella catarrhalis RH4 chromosome, complete genomemolybdenum cofactor biosynthesis protein C8e-2096.3
NC_013947:6678000:667804966780496678522474Stackebrandtia nassauensis DSM 44728 chromosome, complete genomemolybdenum cofactor biosynthesis protein C1e-1995.5
NC_016010:1169850:117385111738511174348498Xanthomonas axonopodis pv. citrumelo F1 chromosome, completemolybdenum cofactor biosynthesis protein MoaC1e-1995.5
NC_015587:114684:122887122887123795909Hydrogenobaculum sp. SHO chromosome, complete genomemolybdenum cofactor biosynthesis protein C2e-1995.1
NC_020411:114683:122886122886123794909Hydrogenobaculum sp. HO, complete genomemolybdenum cofactor biosynthesis protein C2e-1995.1
NC_015557:114648:122851122851123759909Hydrogenobaculum sp. 3684 chromosome, complete genomemolybdenum cofactor biosynthesis protein C2e-1995.1
NC_015474:328500:344039344039344533495Pyrococcus sp. NA2 chromosome, complete genomeputative molybdenum cofactor biosynthesis protein C2e-1994.7
NC_014008:354292:388276388276388749474Coraliomargarita akajimensis DSM 45221 chromosome, complete genomemolybdenum cofactor biosynthesis protein C7e-1993.2
NC_007164:1839154:186616618661661866636471Corynebacterium jeikeium K411, complete genomemolybdenum cofactor biosynthesis protein1e-1892.8
NC_013406:5954472:597503159750315975507477Paenibacillus sp. Y412MC10 chromosome, complete genomemolybdenum cofactor biosynthesis protein C1e-1892.8
NC_014926:819163:835770835770836681912Thermovibrio ammonificans HB-1 chromosome, complete genomemolybdenum cofactor biosynthesis protein C3e-1891.3
NC_018643:320197:334084334084334629546Alpha proteobacterium HIMB5 chromosome, complete genomecyclic pyranopterin monophosphate synthase subunit MoaC1e-1789
NC_015216:1941000:196303319630331963503471Methanobacterium sp. AL-21 chromosome, complete genomemolybdenum cofactor biosynthesis protein C5e-1787
NC_013222:432947:439383439383439817435Robiginitalea biformata HTCC2501, complete genomemolybdenum cofactor biosynthesis protein C6e-1683.6
NC_008571:505776:523159523159524055897Gramella forsetii KT0803, complete genomemolybdenum cofactor biosynthesis bifunctional pr otein1e-1582.4
NC_012726:1263927:128482212848221285271450Sulfolobus islandicus M.16.4 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC9e-1579.3
NC_010943:2815865:281853328185332819498966Stenotrophomonas maltophilia K279a, complete genomeputative molybdenum cofactor biosynthesis protein (putative secreted protein)2e-1375.1
NC_019791:638500:645690645690646130441Caldisphaera lagunensis DSM 15908 chromosome, complete genomemolybdenum cofactor biosynthesis protein MoaC2e-1168.6
NC_009954:117895:1310881310881320891002Caldivirga maquilingensis IC-167, complete genomemolybdopterin cofactor biosynthesis MoaC region6e-1063.5